|
Complement C1, Human
Native, human C1 complement component. C1 is the first component of the classical complement pathway. It is a calcium-dependent complex of C1q, C1r, and C1s subcomponents which are present in the C1 complex at molar ratios of 1:2:2, respectively. Binding of C1 to classical pathway activators results in the conversion of the proenzyme C1s subcomponent to an active C1s enzyme. C1s enzyme cleaves both C4 and C2 resulting in formation of the C3 cleaving enzyme, C4b, C2a, of the classical complement pathway. C1 concentration is based on functional activity measurements relative to a normal serum standard pool.
产品信息
Form Liquid
Formulation In 300 mM NaCl, 50 mM sodium acetate, 50 mM EACA, 25 µM NPGB, 10 mM benzamidine, 10 mM EDTA, 40% glycerol, pH 5.5.
Avoid freeze/thaw 是的
Source Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
商店和运输信息
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling |