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Anthrax Lethal Factor, Recombinant, Bacillus anthracis, B. anthracis
Recombinant, Bacillus anthracis anthrax lethal factor expressed in a specialized strain of B. anthracis. One of the three protein components of Anthrax toxin, lethal factor (LF) is a highly specific protease that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) family. LF is comprised of four domains. Domain I binds the protective antigen to enter the target cell; domains II, III, and IV create a long groove to hold and cleave the MAPKK proteins.
产品信息
Form Lyophilized
Formulation Lyophilized from 50 mM NaCl, 5 mM HEPES, pH 7.5.
Primary Target MAPKK
Molar mass 90000
Unit definition One unit is defined as the amount of enzyme required to catalyze the release of 1.0 pmole of cleaved MAPKKide™ substrate per min at 37°C, in 20 mM HEPES, pH 8.2.
Purity Single major band by SDS-PAGE
Solubility Sterile dH2O
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
End use certificate To purchase this product, the completion of a "Select Agent Declaration" and/or "End-Use Certificate" is required. Once your sales order is placed, our Regulatory Specialist will be contacting the end-user of this product to complete the required form(s). Please ensure to provide the customer service representative with the end-user's name, telephone number, fax number and e-mail address to prevent delivery delays. (Note: the completed form must be returned within five (5) business days from receipt and will be valid for one year from the date of signing.) |