ANISOMYCIN, STREPTOMYCES GRISEOLUS

Anisomycin, Streptomyces griseolus
2-(p-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate
Strongly activates stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase in mammalian cells. Synergizes with growth factors to induce c-fos and c-jun by acting as a potent signaling agonist. An inhibitor of protein synthesis at the translation step. Also known to induce apoptosis in the human monoblastoid cell line, U937.
产品信息
Form  White solid
Molar mass  265.3
Purity  ≥98% by TLC
Solubility  DMSO or MeOH
Chemical formula  C14H19NO4
RTECS  BZ9800000
CAS number  22862-76-6
Merck USA index 14, 670
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Toxic
安全标示
S Phrase  S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase  R: 23/24/25
Toxic by inhalation, in contact with skin and if swallowed.