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2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release. Inhibits Ins(1,4,5)P3-induced Ca2+ release from rat cerebellar microsomal preparations (IC50 = 42 µM) without affecting [3H]-Ins(1,4,5)P3 binding to its receptor. Does not affect Ca2+ release from the ryanodine-sensitive Ca2+ store in rat leg skeletal muscle and heart. Inhibits spontaneous as well as the phasic contractions induced by uterotonic agents. Also reported to inhibit angiotensin II-induced contractions in aortic muscles.
产品信息
Form White crystalline solid
Molar mass 225.1
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥97% by titration
Solubility DMSO or EtOH
Chemical formula C14H16BNO
RTECS ED6150000
CAS number 524-95-8
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |