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A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). Suitable for use in both in vitro and in vivo systems. Has a protective effect against cerebral ischemia by reducing ischemic lesion volumes. Exhibits greater than 5000- and 200-fold potency against human iNOS relative to eNOS and nNOS, respectively, and greater than 1000-fold potency against rat iNOS relative to eNOS.
产品信息
Form White solid
Primary Target iNOS
Primary Target Ki kd = 7 nM
Molar mass 250.2
Hygrocopic 是的
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥95% by HPLC
Solubility MeOH or H2O
Chemical formula C10H15N3 · 2HCl
CAS number 214358-33-5
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |