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Beta-Catenin [pY86] Mouse mAb (clone 24 E1)
The α-, β- and γ-catenins are cytoplasmic proteins mediating the interaction of Ca2+-dependent transmembrane adhesion molecules (cadherins) with the cytoskeletal network. The direct interaction of β-catenin with the cytoplasmic domain of cadherins plays a crucial role for cell-cell adhesion and signal transmission between neighboring cells.
Isotype: Mouse IgG1
Clone/PAD: b-Cat-24E1
Immunogen: Phosphopeptide containing amino acid sequence DGQ[pY]AMT, conjugated to hemocyanin.
Specificity: This antibody specifically recognizes β-catenin phosphorylated at tyrosine 86 (90 kDa).
Reactivity: Cn, Hu, Ms
Applications: E, WB
Reactivity: Human,
Mouse
Validated Application: Western Blot,
ELISA
Host: Mouse
Clonality: Monoclonal
Clone ID: 24 E1
Target Gene: Catenin beta [pY86]
Gene ID: 1499, 12387
Label or Dye: Unconjugated
Target Modification State: Phospho
Product Size: 50 µL
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C). |