DYNABEADS CD45

Dynabeads® CD45
Dynabeads® CD45 are superparamagnetic beads covalently coupled to anti-human CD45 antibody that enable isolation or depletion of CD45+ leucocytes directly from whole blood, buffy coat, or MNC suspensions. Dynabeads® CD45 can also be used to enrich epithelial tumor cells. The CD45 antigen is weakly expressed on myeloid cells. To efficiently deplete or isolate all leucocytes including myeloid cells, use Dynabeads® CD15 (Cat. No. 11137D) in combination with Dynabeads® CD45. Advantages of Dynabeads® CD45:
• Efficient depletion of human leucocytes
• Isolation of leucocytes directly from whole blood for molecular applications
• Enrichment of circulating epithelial tumor cells
About Dynabeads® CD45
Dynabeads® CD45 are uniform, superparamagnetic beads (4.5 µm diameter) coated with a primary monoclonal mouse IgG2a antibody specific for a CD45 membrane antigen common to all known isoforms of CD45. CD45 is expressed on all human leucocytes. Because of the bead size, Dynabeads® CD45
Capacity: Processes ~5x10^8 cells total 
Cell Type: Tumor Cells,
Leukocytes 
Product Size: 5 mL 
Target Species: Human 
Isolation Method: Depletion, positive isolation for molecular applications 
Output Viability: >95% 
Sample Type (Specific): PBMC,
Blood
Starting Material (Cell #): 1x10^7 PBMCs per isolation 
Shipping Condition: Room Temperature
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
This Product Contains: 5 ml Dynabeads® CD45 coated with anti-CD45 monoclonal antibody.
Storage Conditions: 2°C to 8°C. Do not freeze.