|
Human FGF-23 ELISA Kit
Description:
Human FGF-23 ELISA Kit
Qty/Pk:
96-well plate
Background Information:
Studies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.
View All »
Applications:
This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.
Key Applications:
ELISA
Application Notes:
50µl sample size, 2-Step assay with <4hr incubation time.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Linearity of Dilution:
Please contact Technical Service for this information
Sensitivity:
Sensitivity in Tissue Culture/Serum/Plasma*:
9.9 pg/ml
*Minimum Detectable Concentrations
Standard Curve Range:
9.9 – 2400 pg/mL
Product Name:
Human FGF-23 ELISA Kit
Specificity:
The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.
No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
Analytes Available:
FGF-23
Precision, %:
Intra-assay: < 11%
Inter-assay: < 11%
Detection Methods:
Colorimetric
Fluorescent
Accuracy:
Spike/Recovery: 76-101% |