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Human FGF-21 ELISA Kit
Description:
Human FGF-21 ELISA Kit
Qty/Pk:
96-well strip plate
Background Information:
Recent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
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Applications:
This Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
Key Applications:
ELISA
Application Notes:
This is a 3-hour assay requiring 50 μL of sample.
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Linearity of Dilution:
Please contact Technical Service for this information
Standard Curve Range:
31.3– 2000 pg/mL
Product Name:
Human FGF-21 ELISA Kit
Specificity:
No significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
Analytes Available:
FGF-21
Precision, %:
Intra-assay: < 6%
Inter-assay: < 9%
Detection Methods:
Fluorescent
Colorimetric
Accuracy:
83 – 99% |