|
Anti-Ubiquitin (CT) Antibody, rabbit monoclonal
Close
REFERENCES
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.
Shinichiro Nakada,Ikue Tai,Stephanie Panier,Abdallah Al-Hakim,Shun-Ichiro Iemura,Yu-Chi Juang,Lara O'Donnell,Ayako Kumakubo,Meagan Munro,Frank Sicheri,Anne-Claude Gingras,Tohru Natsume,Toshio Suda,Daniel Durocher (2010) Nature.466
Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells
Goldstein, G, et al (1975) Proc Natl Acad Sci USA, 72:11-5 (1975)
Multiple forms of ubiquitin-activating enzyme E1 from wheat. Identification of an essential cysteine by in vitro mutagenesis
Hatfield, P M and Vierstra, R D (1992) J Biol Chem, 267:14799-803 (1992)
Species Reactivity Key Applications Host Format Antibody Type
H, M, R WB Rabbit Purified Monoclonal Antibody
Description:
Anti-Ubiquitin (CT) Antibody, rabbit monoclonal
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
Recognizes a region composed of residues at the C-terminus of human Ubiquitin.
Molecular Weight:
8.5kDa
Immunogen:
KLH-conjugated synthetic peptide composed of residues at the C-terminus of human Ubiquitin.
Isotype:
IgG
Species Reactivity:
Human
Mouse
Rat
Quality Assurance:
Routinely evaluated by immunoblot.
Presentation:
In 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol.
Storage Conditions:
2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.
View All »
UniProt Number:
P62988
Entrez Gene Number:
NM_002954.3
Gene Symbol:
RPS27A
CEP80
ubiquitin
ubiquitin-CEP80
UBCEP1
Ubiquitin.
UBA52
UBCEP2
UBA80
UBC
UBB
HUBCEP80
View All »
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Western Blotting
Entrez Gene Summary:
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
View All »
UniProt Summary:
FUNCTION: SwissProt: P629 |