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Virstatin
Inhibits virulence regulation in V. cholerae. Prevents expression of cholera toxin and the toxin coregulated pilus (TCP) by inhibiting the transcriptional regulator ToxT. Effectively protects infant mice against TCP-dependent V. cholerae intestinal colonization in vivo. Displays little toxicity towards mammalian cells (up to 2mM for Hep2 cells).
Product Specification
Alternative Name: 4-(N-(1,8-Naphthalimide))-n-butyric acid, 1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-butanoic acid
Formula: C16H13NO4
MW: 283.3
CAS: 88909-96-0
Purity: ≥97% (HPLC)
Appearance: Off-white to yellow solid.
Hazard: HARMFUL.
Solubility: Soluble in DMSO.
Long Term Storage: -20°C
Use/Stability: Stock solutions are stable for up to 6 months when stored at -20°C.
Handling: Protect from light. |