Human PDGF-AA

PDGF-AA, human recombinant
A growth factor that regulates cell growth and division
Product Overview
Alternate Names / Synonyms: Human PDGF-AA, h-PDGF-AA, PDGFAA, PDGF AA, PDGF-AA, rh-PDGF-AA, recombinant human PDGF-AA, recombinant PDGF-AA, PDGF
Gene Symbol: PDGFA
Accession #: P04085
Gene ID: 5154
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 28.5 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: 0.01 ng/μg
Biological Activity: The activity is calculated by the dose-dependent proliferation of mouse 3T3 indicator cells and is typically 3 – 5 ng/ml.
Reconstitution Instructions: Reconstitution in 10 mM acetic acid to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-AA is a 28.5 kDa A chain homodimer protein containing 250 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.