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IL-17E, human recombinant
A proinflammatory cytokine produced by activated T cells
Product Overview
Alternate Names / Synonyms: Human IL-17E, IL-17E, IL 17E, IL 17E, h-IL-17E, rh-IL-17E, recombinant human IL-17E, recombinant IL-17, IL-17, interluekin-17
Gene Symbol: IL17-E
Accession #: Q9H293
Gene ID: 64806
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 33.8 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: N/A
Reconstitution Instructions: The lyophilized IL-17E can be reconstituted in water to a concentration of 0.1 µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |