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Prostaglandin D Synthase (lipocalin-type; human) EIA Kit
Cayman Chemical Item Number 10007684
Description
Limit of detection:1.56 ng/ml · Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2, a potent lipid mediator involved in sleep regulation, nociception, platelet aggregation, and allergic and inflammatory responses. Lipocalin-type PGDS (a.k.a. β-trace) is a homodimer with each subunit ranging in size from 20-31 kDa, depending on the extent of glycosylation. L-PGDS has two functions: it catalyzes the conversion of PGH2 to PGD2 and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones).1↗ L-PGDS is present in a variety of body fluids including cerebrospinal fluid, seminal fluid, and plasma. Cayman’s L-PGDS (human) EIA is an immunometric (i.e., sandwich) EIA with a standard curve ranging from 0-100 ng/ml and a limit of detection of 1.56 ng/ml. Inter- and intra-assay CV’s of less than 15% may be achieved at most concentrations. This assay has been validated using cerebrospinal fluid which contains approximately 12-30 µg/ml of L-PGDS.
Synonyms
L-PGDS EIA Kit
Lipocalin-PGDS ELISA Kit
Stability 1 year
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Prostaglandin D Synthase (lipocalin-type; human) 100% |