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N-Arachidonoyl TaurineExclusive
Cayman Chemical Item Number 10005537
Description
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl-L-serine (ARA-S), have been isolated and characterized from bovine brain.1↗ During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered.2↗ This novel class or compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3↗ N-arachidonoyl taurine, a prominent N-acyl taurine, activates both TRPV1 and TRPV4 with EC50 values of 28 and 21 µM, respectively.3↗
Formal Name 2-[(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)amino]-ethane sulfonic acid
CAS Number 119959-65-8
Molecular Formula C22H37NO4S
Formula Weight 411.6
Formulation A crystalline solid
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(N(CCS(=O)(O)=O)[H])=O
InCHI Code 1S/C22H37NO4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(24)23-20-21-28(25,26)27/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)(H,25,26,27)/b7-6-,10-9-,13-12-,16-15-
InCHI Key YUNYSWCRLRYOPO-DOFZRALJSA-N |