Functional Aspects:ret Oncoprotein is a cell surface glycoprotein in the receptor tyrosine kinase family. Three main 3’ splice isoforms are known and ret expression is found in several regions of the CNS and in growing tips of collecting ducts in developing kidney. Mutations of the ret protooncogene are implicated in certain developmental abnormalities and tumors. This antibody will help detect all isoforms of ret oncoprotein in normal and uncharacterized tissues.
