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Leupeptin
Description:
Leupeptin
Trade Name:
Chemicon (Millipore)
Qty/Pk:
100 mg
Product Overview:
Leupeptin is an organic compound produced by actinomycetes, serine and cysteine proteases reversibly. Inhibits trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, Kallikrein, papain, thrombin, cathepsin B and trypsin.
MW:426.56 s 49.04 . 18.02 {C20H36N6O4 . ½H2SO4 . H2O}
Ac-Leu-Leu-Argininal (hemi-sulfated form). Thus material has three tautomeric isomers that can be visualized by chromatography.
Appearance: Colorless amorphous powder
Unit: 843μg/mg
Working range 10-100μM. Stable for several hours in water. Stock solutions of 10mM in water are stable for 1 week at 4ºC and 6 months at -20ºC.
Specific Activity: IC50: 1.2 μg/mL (trypsin/TAME, pH 8.1, 30ºC)
5mg/1.054 mL = 10mM. Typically dilute 1:100 for a 100μM working solution.
Source: Organic isolated from actinomycetes.
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Key Applications:
Inhibits Activity/Function
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Brand Family:
Chemicon
Presentation:
Lyophilized.
Storage Conditions:
Maintain dry at -20ºC for up to 18 months after date of receipt. Store reconstituted product in aliquots at -20ºC for up to 6 months. Avoid repeated thaw freeze cycles.
Product Name:
Leupeptin |