Elastase Inhibitor V A benzoxazinone compound that acts as a potent inhibitor of human leukocyte elastase (IC50 = 29.5 nM), likely by covalently modifying active site serine. Shown to inhibit elastase secretion (IC50 = 80.8 nM), but not O2•- generation, in fLMP (Cat. No. 05-22-2500)-stimulated primary human neutrophil cultures. Reported to reduce neutrophil infiltration in lung after hemorrhagic shock in rats in vivo (1 mg/kg, i.v.). 产品信息 Form Off-white solid Primary Target Elastase Molar mass 336.6 Protect from Light 是的 Protect from Moisture 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥99% by HPLC Solubility DMSO 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling