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Relaxin-2, human recombinant
Enhances the growth of pubic ligaments and ripening of the cervix during birth
Product Overview
Product Name: Relaxin-2, human recombinant
Alternate Name/Synonyms: H2 relaxin, RLN2
Gene Symbol: RLN2
Accession #: P04090
Gene ID: 6019
Source: E. Coli
Appearance: Lyophilized powder
Physical Form Description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
Molecular Weight: 6.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: < 0.1 ng/μg of protein (<1EU/μg).
Biological Activity: N/A
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.
Amino Acid Sequence: A Chain: QLYSALANKC CHVGCTKRSL ARFC B Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |