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SAA1 monkey, recombinant
An acute phase apolipoprotein reactant
Product Overview
Alternate Name/Synonyms: Monkey SAA1, SAA1, r-SAA1, rm-SAA1, recombinant monkey SAA1, recombinant SAA1, Serum amyloid A protein, SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2, PIG4, TP53I4, MGC111216, recombinant Serum amyloid A protein
Gene Symbol: SAA
Accession #: P02738
Gene ID: Ensembl: ENSMMUT00000015626
Source: E. Coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from a sterile filtered solution containing PBS pH 7.4
Molecular Weight: 11.8 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: N/A
Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml
Reconstitution Instructions: Reconstitute in sterile ddH₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues; it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. SAA1 monkey recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 104 amino acids and having a total molecular mass of 11.8 kDa. SAA1 is purified by proprietary chromatographic techniques
Amino Acid Sequence: RSWFSFLGEA YDGARDMWRA YSDMKEANYK NSDKYFHARG NYDAAQRGPG GVWAAEVISD ARENIQKLLG RGAEDTLADQ AANEWGRSGK DPNHFRPAGL PEKY
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |