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CEP-18770
A potent proteosome inhibitor
Product Overview
Product Name: CEP-18770
Alternate Name/Synonyms: [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid
Description: CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 847499-27-8
Molecular Formula: C21H28BN3O5
Molecular Weight: 413.28
Purity: ≥98% by HPLC
Solubility:DMSO (>70 mg/ml) or EtOH (>70 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and mositure
SMILES: B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
InChi: InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
InChi Key: SJFBTAPEPRWNKH-CCKFTAQKSA-N
PubChem CID: 24800541
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |