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Cryptotanshinone
A STAT3 inhibitor
Product Overview
Product Name: Cryptotanshinone
Alternate Name/Synonyms: 1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione
Description: Cryptotanshinone is a natural product isolated from the roots of Salvia miltiorrhiza Bunge that displays a variety of biological activities. Displays antitumor activity by inhibition of STAT3 (IC₅₀ = 4.6 µM). Also displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also inhibits acetylcholinesterase (AChE) (IC₅₀ = 4.09 μM) and reduction in Aβ peptide generation.
Peptide Sequence: N/A
Appearance: Orange solid
Formulation: N/A
CAS Number: 35825-57-1
Molecular Formula: C19H20O3
Molecular Weight: 296.36
Purity: ≥98% by HPLC
Solubility:DMSO (~ 5 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
InChi: InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
InChi Key: GVKKJJOMQCNPGB-JTQLQIEISA-N
PubChem CID: 160254
MDL Number: MFCD07636810
USAGE: For Research Use Only! Not For Use in Humans. |