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Phytosphingosine
An apoptosis inducer
Product Overview
Product Name: Phytosphingosine
Alternate Name/Synonyms: 4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS
Description: Phytosphingosine is a phospholipid structurally similar to Sphingosine (Cat. No. 2425). The physiological roles of phytosphingosine are largely unknown. Phytosphingosine induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells, and induces caspase-independent cytochrome c release from mitochondria. In the presence of caspase inhibitors, phytosphingosine-induced apoptosis is almost completely suppressed, suggesting that phytosphingosine-induced apoptosis is largely dependent on caspase activities.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 554-62-1
Molecular Formula: C18H39NO3
Molecular Weight: 317.51
Purity: ≥98% by TLC
Solubility:EtOH (~ 2 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCCCCCCCCCCCCCC(C(C(CO)N)O)O
InChi: InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChi Key: AERBNCYCJBRYDG-KSZLIROESA-N
PubChem CID: 122121
MDL Number: MFCD06804643
USAGE: For Research Use Only! Not For Use in Humans. |