AKR1C3 Inhibitor III A potent and selective AKR1C3 inhibitor Product Overview Product Name: AKR1C3 Inhibitor III Alternate Name/Synonyms: 4-(4-Chlorophenyl)piperazin-1-yl)(morpholino)methanone Description: A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 88 nM). Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4. Does not display any COX (cyclooxygenase) inhibition at 10 µM in whole blood assay. Peptide Sequence: No Appearance: White to off-white solid Formulation: N/A CAS Number: N/A Molecular Formula: C15H20ClN3O2 Molecular Weight: 309.79 Purity: ≥98% by HPLC Solubility:DMSO Storage Temp.: -20 ̊C Shipping Conditions: gel pack Handling: Protect from air and light SMILES: O=C(N1CCN(C2=CC=C(Cl)C=C2)CC1)N3CCOCC3 InChi: InChI=1S/C15H20ClN3O2/c16-13-1-3-14(4-2-13)17-5-7-18(8-6-17)15(20)19-9-11-21-12-10-19/h1-4H,5-12H2 InChi Key: KDSIRFZJOTZBPT-UHFFFAOYSA-N PubChem CID: N/A MDL Number: N/A USAGE: For Research Use Only! Not For Use in Humans.
