|
Aconitine
Sodium channel opener
Product Overview
Product Name: Aconitine
Alternate Name/Synonyms: (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate; Acetylbenzoylaconine
Description: Aconitine is diterpene alkaloid derived from the tubers of aconitinum plants. It is a neurotoxin that opens TTX(tetrodotoxin)-sensitive Na⁺ channels in the heart and other tissues, and is used for creating models of cardiac arrhythmia. Aconitine was previously used as an antipyretic and analgesic, and still has some limited application in herbal medicine.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 302-27-2
Molecular Formula: C34H47NO11
Molecular Weight: 645.75
Purity: ≥98% by HPLC
Solubility:EtOH (~ 35 mg/ml) or H₂O (~0.3 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC
InChi: InChI=1S/C34H47NO11/c1-7-35-15-31(16-41-3)20(37)13-21(42-4)33-19-14-32(40)28(45-30(39)18-11-9-8-10-12-18)22(19)34(46-17(2)36,27(38)29(32)44-6)23(26(33)35)24(43-5)25(31)33/h8-12,19-29,37-38,40H,7,13-16H2,1-6H3/t19-,20-,21+,22-,23+,24+,25-,26?,27+,28-,29+,31+,32-,33+,34-/m1/s1
InChi Key: XFSBVAOIAHNAPC-XTHSEXKGSA-N
PubChem CID: 245005
MDL Number: MFCD00082375
USAGE: For Research Use Only! Not For Use in Humans. |