|
1,5-Isoquinolinediol
A poly(ADP-ribose) synthetase (PARP1) inhibitor
Product Overview
Product Name: 1,5-Isoquinolinediol
Alternate Name/Synonyms: 1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ; NSC 65585
Description: 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC₅₀ = 0.39 μM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. Also acts as a neuroprotective agent.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1188540
Molecular Formula: C9H7NO2
Molecular Weight: 161.16
Purity: ≥98% by TLC
Solubility:DMSO (>35 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: C1=CC2=C(C=CNC2=O)C(=C1)O
InChi: InChI=1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-10-9(7)12/h1-5,11H,(H,10,12)
InChi Key: LFUJIPVWTMGYDG-UHFFFAOYSA-N
PubChem CID: 1340
MDL Number: MFCD00006900
USAGE: For Research Use Only! Not For Use in Humans. |