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GSK-3787
A potent PPARδ antagonist
Product Overview
Product Name: GSK-3787
Alternate Name/Synonyms: 4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Description: GSK-3787 is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) (plC₅₀ = 6.6). It covalently binds to Cys 249 in the PPARδ binding site.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 188591-46-0
Molecular Formula: C15H12ClF3N2O3S
Molecular Weight: 392.78
Purity: ≥98% by TLC
Solubility:DMSO (~30 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: C1=CC(=CC=C1C(=O)NCCS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)Cl
InChi: InChI=1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23,24)13-6-3-11(9-21-13)15(17,18)19/h1-6,9H,7-8H2,(H,20,22)
InChi Key: JFUIMTGOQCQTPF-UHFFFAOYSA-N
PubChem CID: 2800647
MDL Number: MFCD00099612
USAGE: For Research Use Only! Not For Use in Humans. |