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Epalrestat
An aldose reductase inhibitor
Product Overview
Product Name: Epalrestat
Alternate Name/Synonyms: 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
Description: Epalrestat is an aldose reductase inhibitor (IC₅₀ = 10 nM (rat lens) and 25 nM (human placenta). It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 82159-09-9
Molecular Formula: C15H13NO3S2
Molecular Weight: 319.4
Purity: ≥98% by TLC
Solubility:DMSO (~5 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CC(=CC1=CC=CC=C1)C=C2C(=O)N(C(=S)S2)CC(=O)O
InChi: InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
InChi Key: CHNUOJQWGUIOLD-NFZZJPOKSA-N
PubChem CID: 1549120
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |