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Andrographolide
A NF-kappa B activation inhibitor
Product Overview
Product Name: Andrographolide
Alternate Name/Synonyms:
Description: A major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-apoptotic, anti-viral and anti-proliferative effects in vitro and in vivo. Prevents hyperglycemia in rat diabetes model. Irreversible antagonist of NK-κB and AP-1 (IC₅₀ = 15 µM).
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 5508-58-7
Molecular Formula: C20H30O6
Molecular Weight: 350.45
Purity: ≥98% by NMR
Solubility:DMSO (~25 mg/ml) or EtOH (~ 8 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and air
SMILES: CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O
InChi: InChI=1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
InChi Key: BOJKULTULYSRAS-OTESTREVSA-N
PubChem CID: 5318517
MDL Number: MFCD07778082
USAGE: For Research Use Only! Not For Use in Humans. |