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AZD-3463
A potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor
Product Overview
Product Name: AZD-3463
Alternate Name/Synonyms: 2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl
Description: AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1356962-20-3
Molecular Formula: C24H25ClN6O
Molecular Weight: 448.95
Purity: ≥98% by HPLC
Solubility:DMSO (~20 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
InChi: InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)
InChi Key: GCYIGMXOIWJGBU-UHFFFAOYSA-N
PubChem CID: 56599293
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |