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7-Nitroindazole
A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro.
Product Overview
Product Name: 7-Nitroindazole
Alternate Name/Synonyms: 7-nitro-1H-indazole; 7-NI
Description: A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS.
Peptide Sequence: N/A
Appearance: Brown solid
Formulation: N/A
CAS Number: 2942-42-9
Molecular Formula: C7H5N3O2
Molecular Weight: 163.13
Purity: ≥97% by GC
Solubility:DMSO (~ 15 mg/ml) or EtOH (~4 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2
InChi: InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
InChi Key: PQCAUHUKTBHUSA-UHFFFAOYSA-N
PubChem CID: 1893
MDL Number: MFCD00022789
USAGE: For Research Use Only! Not For Use in Humans. |