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BEC
A potent arginase inhibitor
Product Overview
Product Name: BEC
Alternate Name/Synonyms: S-(2-boronoethyl)-L-cysteine
Description: A potent, slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 µM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 µM and 30 nM at pH 7.5 and 9.5, respectively. It does not inhibit murine iNOS at concentrations up to 1 mM. BEC significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 63107-40-4
Molecular Formula: C5H12BNO4S
Molecular Weight: 193.03
Purity: ≥98%
Solubility:PBS, pH 7.2 (~ 5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: B(CCSCC(C(=O)O)N)(O)O
InChi: InChI=1S/C5H12BNO4S/c7-4(5(8)9)3-12-2-1-6(10)11/h4,10-11H,1-3,7H2,(H,8,9)/t4-/m0/s1
InChi Key: OTJHLDXXJHAZTN-BYPYZUCNSA-N
PubChem CID: 9877608
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |