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您现在的位置:产品中心 >>
细胞生物学 >> 细胞凋亡 |
Torin 2, EZSolution?
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产品编号: |
2354-5
查看说明书 |
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产品名称:
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Torin 2, EZSolution? .0 订购此产品 |
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供应商:
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Biovision |
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规格: |
5 mg |
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目录价: |
1875 |
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库存状态: |
3周到货 |
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CAS编号:
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1222998-36-8 |
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应用范围: |
生化实验 |
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种属来源: |
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相关信息: |
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EZSolution™ Torin 1
A potent mTOR inhibitor
Product Overview
Product Name: EZSolution™ Torin 1
Alternate Name/Synonyms: 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one
Description: A potent, selective and ATP-competitive mTOR inhibitor, with IC₅₀ values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC₅₀ = 1800 nM) and exhibits 100-fold binding selectivity relative to 450 other protein kinases.
Peptide Sequence: N/A
Appearance: Liquid
Formulation: A 10 mM solution in DMSO
CAS Number: 1222998-36-8
Molecular Formula: C35H28F3N5O2
Molecular Weight: 607.62
Purity: ≥98% by HPLC
Solubility:N/A
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
InChi: InChI=1S/C35H28F3N5O2/c1-2-32(44)42-15-13-41(14-16-42)31-11-9-26(19-28(31)35(36,37)38)43-33(45)12-8-24-20-40-30-10-7-22(18-27(30)34(24)43)25-17-23-5-3-4-6-29(23)39-21-25/h3-12,17-21H,2,13-16H2,1H3
InChi Key: AKCRNFFTGXBONI-UHFFFAOYSA-N
PubChem CID: 49836027
MDL Number: MFCD18782653
USAGE: For Research Use Only! Not For Use in Humans. |
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保存条件: |
-20°C |
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说明书地址: |
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