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KH7
A selective inhibitor of soluble adenylyl cyclase (sAC)
Product Overview
Product Name: KH7
Alternate Name/Synonyms: 2-(1H-benzimidazol-2-ylthio)-2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide, propanoic acid
Description: A selective inhibitor of soluble adenylyl cyclase (sAC) ( IC₅₀ = 3-10 µM in vivo). Displays little effect on transmembrane adenylyl cyclases. KH7 is not active against sAC in the presence of detergents. At concentrations above 50 µM, KH7 exhibits non-specific membrane disruption effects when used on cells.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 330676-02-3
Molecular Formula: C17H15BrN4O2S
Molecular Weight: 419.3
Purity: ≥98%
Solubility:DMSO (~40 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(C(=O)NNC=C1C=C(C=CC1=O)Br)SC2=NC3=CC=CC=C3N2
InChi: InChI=1S/C17H15BrN4O2S/c1-10(25-17-20-13-4-2-3-5-14(13)21-17)16(24)22-19-9-11-8-12(18)6-7-15(11)23/h2-10,19H,1H3,(H,20,21)(H,22,24)
InChi Key: GEHVZUUHMWNMAY-UHFFFAOYSA-N
PubChem CID: 6843191
MDL Number: MFCD01230899
USAGE: For Research Use Only! Not For Use in Humans. |