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DTSSP Crosslinker
A cleavable homobifunctional protein crosslinking reagent
Product Overview
Product Name: DTSSP Crosslinker
Alternate Name/Synonyms: 1-[3-[3-(2,5-dioxo-3-sulfopyrrolidin-1-yl)oxy-3- oxopropyl]disulfanylpropanoyloxy]-2,5-dioxopyrrolidine-3-sulfonic acid; Sulfo-DSP; DTBSSP
Description: KEY FEATURES & APPLICATIONS:
• Water-soluble
• Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends
• Contains cleavable, 8-atom (12 Å) spacer arm
• The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc.
• DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 81069-02-5
Molecular Formula: C₁₄H₁₄O₁₄N₂S₄Na₂
Molecular Weight: 608.51
Purity: ≥80% by NMR
Solubility:H₂O (>6 mg/ml)
Storage Temp.: +4 ̊C
Shipping Conditions: Gel Pack
Handling: Protect from air and light
SMILES: CN(OC(CCSSCCC(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)=O)=O)C(CS(=O)(O[Na])=O)=O
InChi: InChI=1S/C13H18N2O13S4.2Na/c1-14(10(17)7-31(21,22)23)27-11(18)2-4-29-30-5-3-12(19)28-15-9(16)6-8(13(15)20)32(24,25)26;;/h8H,2-7H2,1H3,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
InChi Key: LFRKLPYHXPWFCL-UHFFFAOYSA-L
PubChem CID: 123933
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |