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Sulfo-NHS-SS-Biotin
A water-soluble, dislulfide-reducible, protein biotinylation reagent.
Product Overview
Product Name: Sulfo-NHS-SS-Biotin
Alternate Name/Synonyms: Sulfosuccinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate; Biotin disulfide N-Hydroxysulfosuccinimide ester
Description: KEY FEATURES:
• Sulfo-NHS-SS-Biotin is amine-reactive and
• Has a long chain spacer arm (24.3 Å) separating the biotin group from the amino-reactive sulfo-NHS ester
• Water-soluble; can be used under physiologic conditions
• It is possible to cleave the biotin group from the cross-linked target protein under reducing conditions, such as in the presence of BME, DTT or TCEP
APPLICATIONS:
• Sulfo-NHS-SS-Biotin is ideal for biotinylating antibody or protein that can then be used for protein purification, detection or immobilization
• Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins due to the membrane-impermeability of this reagent
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 325143-98-4
Molecular Formula: C₁₉H₂₇O₉N₄S₄Na
Molecular Weight: 606.69
Purity: ≥80% by NMR
Solubility:H₂O (~ 6 mg/ml)
Storage Temp.: +4 ̊C
Shipping Conditions: gel pack
Handling: Protect from moisture
SMILES: O=C(NCCSSCCC(ON1C(C(S(=O)(O[Na])=O)CC1)=O)=O)CCCCC2SCC(C2N3)NC3=O
InChi: InChI=1S/C19H30N4O8S4.Na/c24-15(4-2-1-3-13-17-12(11-32-13)21-19(27)22-17)20-7-10-34-33-9-6-16(25)31-23-8-5-14(18(23)26)35(28,29)30;/h12-14,17H,1-11H2,(H,20,24)(H2,21,22,27)(H,28,29,30);/q;+1/p-1
InChi Key: HBLXCNOBPVOLAK-UHFFFAOYSA-M
PubChem CID: N/A
MDL Number: MFCD00078533
USAGE: For Research Use Only! Not For Use in Humans. |