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Tripolin A
An Aurora kinase A inhibitor
Product Overview
Product Name: Tripolin A
Alternate Name/Synonyms: (3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
Description: A specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 1148118-92-6
Molecular Formula: C₁₅H₁₁NO₃
Molecular Weight: 253.25
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: OC1=CC=C(O)C=C1/C=C(C2=C(N3)C=CC=C2)C3=O
InChi: InChI=1S/C15H11NO3/c17-10-5-6-14(18)9(7-10)8-12-11-3-1-2-4-13(11)16-15(12)19/h1-8,17-18H,(H,16,19)/b12-8-
InChi Key: OMKSBDLWMROKNU-WQLSENKSSA-N
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |