USP7/USP47 Inhibitor, P 22077 A USP7/USP47 inhibitor Product Overview Product Name: USP7/USP47 Inhibitor, P 22077 Alternate Name/Synonyms: 1-(5-(2,4-Difluorophenylthio)-4-nitrothiophen-2-yl)ethanone; DUB inhibitor Description: A cell-permeable inhibitor of the ubiquitin-specific protease (IC₅₀ = 8.6 µM) and the closely related deubiquitinase (DUB) USP47. P22077 displays weak or no inhibition (EC₅₀>50 µM) towards a panel of 14 isopeptidases and other proteases. Inhibits USP7-mediated p53 deubiquitination. Peptide Sequence: No Appearance: Yellow solid Formulation: N/A CAS Number: 1247819-59-5 Molecular Formula: C₁₂H₇F₂NO₃S₂ Molecular Weight: 315.32 Purity: ≥98% by HPLC Solubility:DMSO (~ 30 mg/ml) Storage Temp.: -20 ̊C Shipping Conditions: gel pack Handling: Protect from air and light SMILES: FC1=CC(F)=CC=C1SC2=C([N+]([O-])=O)C=C(C(C)=O)S2 InChi: InChI=1S/C12H7F2NO3S2/c1-6(16)11-5-9(15(17)18)12(20-11)19-10-3-2-7(13)4-8(10)14/h2-5H,1H3 InChi Key: RMAMGGNACJHXHO-UHFFFAOYSA-N PubChem CID: N/A MDL Number: N/A USAGE: For Research Use Only! Not For Use in Humans.
