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680C91
A potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor
Product Overview
Product Name: 680C91
Alternate Name/Synonyms: 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole
Description: Cell-permeable. A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO, Ki = 51 nM.) Tryptophan is metabolized to the endogenous AHR ligand by TDO which may be inhibited by 680C91. Active in vivo.
Peptide Sequence: No
Appearance: Light brown solid
Formulation: N/A
CAS Number: 163239-22-3
Molecular Formula: C₁₅H₁₁FN₂
Molecular Weight: 238.26
Purity: ≥98% by HPLC
Solubility:DMSO (~25 mg/ml) or EtOH (~10 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: C1=CC(=CN=C1)C=CC2=CNC3=C2C=CC(=C3)F
InChi: InChI=1S/C15H11FN2/c16-13-5-6-14-12(10-18-15(14)8-13)4-3-11-2-1-7-17-9-11/h1-10,18H/b4-3+
InChi Key: YBSDQTBCNYWBMX-ONEGZZNKSA-N
PubChem CID: 10014426
MDL Number: MFCD20926361
USAGE: For Research Use Only! Not For Use in Humans. |