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Ferredoxin Reductase Antibody (Clone 6C2)
Monoclonal antibody to detect Ferredoxin Reductase in human samples.
Product Overview
Product Name: Ferredoxin Reductase Antibody (Clone 6C2)
Antibody Target: Ferredoxin Reductase
Alternative Name: NADPH: adrenodoxin oxidoreductase, mitochondrial, FDXR, ADXR
Host: Mouse
Antibody Type: Monoclonal
Isotype: Mouse IgG1
Immunogen: Recombinant human protein purified from E.coli
Accession#: P22570
Gene ID: 2232
Appearance: Colorless liquid
Concentration: 1 mg/ml
Formulation: 100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
Purification: Protein G purified
Species Reactivity: Human
Application: WB
Positive Control: WB: Jurkat, HeLa and 293 T cell lysate
Application & Usage: WB
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Ferredoxin reductase is a ubiquitous flavoenzyme, containing noncovalently bound FAD as a prosthetic group. It plays a role in delivering NADPH or low potential one-electron donors such as ferredoxin and flavodoxin to redox-based metabolisms in plastids, mitochondria and bacteria. In mammals, ferredoxin reductase is loosely associated with the inner mitochondrial membrane and receives electrons from NADPH. These electrons are transferred to ferredoxin which shuttles electrons to cytochrome P450 in the adrenal cortex mitochondrial steroid hydroxylation systems. It serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |