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CD36 FITC Monoclonal Antibody (Clone JC63.1)
Monoclonal FITC conjugated antibody to detect CD36 in human samples.
Product Overview
Product Name: CD36 FITC Monoclonal Antibody (Clone JC63.1)
Antibody Target: CD36
Alternative Name: Platelet glycoprotein 4, Fatty acid translocase, FAT Glycoprotein IIIb, GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein IV, GPIV, Thrombospondin receptor
Host: Mouse
Antibody Type: Monoclonal
Isotype: Mouse IgA
Immunogen: Recombinant adenovirus expressing full-length mouse CD36
Accession#: P16671
Gene ID: 948
Appearance: Colorless liquid
Concentration: 0.2 mg/ml
Formulation: 0.2 mg/ml antibody in PBS with 50% glycerol, 0.5 mg/ml BSA and 0.02% sodium azide.
Purification: Protein G Chromatography purified antibody
Species Reactivity: Human, Mouse, Rat
Application: Flow cytometry and Immunofluorescence, immunoprecipitation and promotion of CD36 function
Positive Control: N/A
Application & Usage: In addition to flow cytometry and immunofluorescence, other reported applications for the JC63.1 clone include immunoprecipitation and promotion of CD36 function
Storage Temp.: -20 °C
Shipping: Gel Pack
Background Descriptions: CD36 is a type-B scavenger receptor that is necessary for the formation of foam cells and thereby atherosclerotic lesions.1,2,3,4 This membrane glycoprotein can internalize fatty acids which activate proliferator-activated receptor ã and stimulate further expression of CD36.5,6 This positive feedback loop combined with the murine CD36 knock-out studies reinforces the importance of CD36 in lipid metabolism. Additionally CD36 is needed for the phagocytosis of P. falciparum infected erythrocytes, retinal pigment epithelial cell photoreceptor fragments and post-apoptotic monocytes and neutrophils.7,8,9,10 CD36 expression has been monitored during hematopoietic cell differentiation and may be an indicator of tumor spreading in lymphocytic leukemia.11 Positive controls include adipose and heart tissue, platelets, and macrophages. Note: mAb clone JC63.1 is also known as clone CRF D-2723 and clone 63.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |