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DNA Methyltransferase 2 (Clone 102B1259.2) Antibody
Monoclonal antibody to detect DNMT2 in Human and Mouse samples
Product Overview
Product Name: DNA Methyltransferase 2 (Clone 102B1259.2) Monoclonal Antibody
Antibody Target: DNA Methyltransferase 2
Alternative Name: DNMT2
Host: Mouse
Antibody Type: Monoclonal
Isotype: Mouse IgG1κ
Immunogen: Synthetic peptides corresponding to mouse DNMT2
Accession#: O55055
Gene ID: 13434
Appearance: Colorless liquid
Concentration: N/A
Formulation: 50 μg of antibody in 100 μl PBS containing 0.2% gelatin and 0.05% sodium azide.
Purification: Protein G purified
Species Reactivity: Human, mouse
Application: Western blot
Positive Control: Western blot: DNMT2 transfected cell lysate
Application & Usage: Western blot: 1-3 μg/ml. However, the optimal conditions should be determined individually.
Storage Temp.: -20 °C
Shipping: Gel Pack
Background Descriptions: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. DNMT2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. DNMT2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.
USAGE: For Research Use Only! Not For Use in Humans. |