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Selumetinib
Description
Selumetinib is a selective inhibitor of MEK1/2. Selumetinib treatment induced G1 cell-cycle arrest and apoptosis and suppression of tumor growth as xenografts in immunodeficient mice.
Specifications
Cas No. 606143-52-6
Product ID S1846
Product Name Selumetinib
Synonym AZD6244, ARRY 142886
Formula C17H15BrClFN4O3
Formula Wt. 457.68
Store Temp Ambient
References Troiani T, Vecchione L, Martinelli E, et al. Br J Cancer. 106(10):1648-59 (2012).
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