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Erlotinib Monohydrochloride
Description
The hydrochloride salt of a quinazoline derivative with anti-neoplastic properties. Competes with ATP, Erlotinib reversibly binds to EGFR tyroside kinase which blocks the signal transduction events and tumorigenic events associated with EGFR activation.
More information about Protein Kinase Inhibitors
Specifications
Product ID E6846
Product Name Erlotinib Monohydrochloride
Formula Wt. 429.9
Melting Point 215-227oC
Solubility 96/4 DMSO/H2O
Store Temp Ambient
References Ali, S. Molecular Cancer Therapeutics (2008), 7(6), 1708-1719. Rudin, C. M. Journal of Clinical Oncology (2008), 26(7), 1119-1127. Burris, H. Oncologist (2008), 13(3), 289-298.
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