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Tacrolimus
Description
An immunosuppressant commonly used in transplant operations to prevent graft-versus-host disease.
Specifications
Cas No. 104987-11-3
Product ID T0008
Product Name Tacrolimus
Chemical Name 3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R, 26aS)5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-5,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclot
Synonym FK-506; Fujimycin; Prograf; Protopic; CCRIS 7124.
Formula Wt. 804.02
Melting Point 126oC
Purity ≥98%
Solubility Soluble in DMSO (>3mg/mL), methanol, ethanol, acetone, ethyl acetate, diethyl ether or chloroform.
Store Temp Ambient
References Sawada S, Suzuki G, Kawase Y et al. J Immunol. 139:1797-1803 (1987).
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