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Human CellExp™ Cystatin C, Human Recombinant
A biomarker of kidney function
Product Overview
Product Name: Human Recombinant Cystatin C
Alternate Name/Synonyms: Cystatin-3, Gamma-trace neuroendocrine basic polypeptide, Post-gamma-globulin
Gene Symbol: CST4
Accession #: P01036
Gene ID: 1472
Source: Human 293 cells
Appearance: Lyophilized protein
Physical Form Description: Lyophilized in PBS
Molecular Weight: 12-13 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: > The inhibitory function of Cystatin C on papin’s protease activity was measured by a colorimetric assay using L-BAPA as substrate. IC50 value was measured at 5 to 20 µg/mL (0.3 to 1.5 µM) with a range of 1.56 µg/mL to 50 µg/mL Cystatin C in presence of 0.55 µM papain and 0.44 µM L-BAPA.
Reconstitution Instructions: Reconstitute in sterile PBS.
Storage Temp.: -80°C
Shipping: Blue ice
Background Information: Xeno-free Cystatin C HuXp (Cys-C) is expressed in human 293 cells as a monomer with an apparent molecular mass of 12 to 13 kDa. Native Cys-C in human urine is found in two different forms: one with pI 9.2 and the other with pI 7.8 by elimination of small basic peptides or amino acids from the N-terminal end of protein. Cystatin C has been studied for its role in predicting new onset or deteriorating cardiovascular disease. This cytokine is produced in a serum-free, chemically defined media.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |