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Human CellExp™ LEFTY-I, Human Recombinant
Plays a role in left-right asymmetry determination of organ systems during development
Product Overview
Product Name: Human Recombinant LEFTY-I
Alternate Name/Synonyms: Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B
Gene Symbol: LEFTY1
Accession #: O75610
Gene ID: 10637
Source: Human 293 cells
Appearance: Lyophilized protein
Physical Form Description: Lyophilized in 10 mM Tris-HCl, pH 7.4, 50 mM NaCl, 0.5% CHAPS.
Molecular Weight: 38 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: The specific activity was determined by dose dependent ability to inhibit BMP-4 (6.5 ng/mL) induction of alkaline phosphatase production in the MC-3T3-E1 cell line (Mouse Chondrogenic cell line).
Reconstitution Instructions: Reconstitute in sterile water.
Storage Temp.: -80°C
Shipping: Blue ice
Background Information: BioVision’s LEFTY-1 is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 38 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media. Lefty proteins function as an antagonist of the Nodal Signaling pathway. Proper functioning of Lefty is crucial to the proper development of the heart, lungs, spleen, and liver..
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans. |