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RANTES, human recombinant
Chemokine for T cells, eosinophils, and basophils
Product Overview
Alternate Names / Synonyms: Human RANTES, RANTES, h-RANTES, rh-RANTES, recombinant human RANTES, recombinant RANTES
Gene Symbol: TCP228
Accession #: P13501
Gene ID: 6352
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 7.8 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1 µg/µl. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°c for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |