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Atpenin A5 (Synthetic)
A potent mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor
Product Overview
Product Name: Atpenin A5 (Synthetic)
Alternate Name/Synonyms: 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone
Description: Synthetic. Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 119509-24-9
Molecular Formula: C₁₅H₂₁Cl₂NO₅
Molecular Weight: 366.24
Purity: ≥95% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC(CC(C)C(=O)C1=C(C(=C(NC1=O)OC)OC)O)C(CCl)Cl
InChi: InChI=1S/C15H21Cl2NO5/c1-7(9(17)6-16)5-8(2)11(19)10-12(20)13(22-3)15(23-4)18-14(10)21/h7-9H,5-6H2,1-4H3,(H2,18,20,21)/t7-,8-,9-/m0/s1
InChi Key: OVULNOOPECCZRG-CIUDSAMLSA-N
PubChem CID: 54676868
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |