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SBHA
A potent HDAC inhibitor
Product Overview
Product Name: SBHA
Alternate Name/Synonyms: Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N'-dihydroxyoctanediamide
Description: SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC₅₀ = 0.25 μM) and HDAC3 (IC₅₀ = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.
Peptide Sequence: N/A
Appearance: White to Off-white Solid
Formulation: N/A
CAS Number: 38937-66-5
Molecular Formula: C₈H₁₆N₂O₄
Molecular Weight: 204.22
Purity: ≥95% by TLC
Solubility:H2O (100 mM) or DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C(CCCC(=O)NO)CCC(=O)NO
InChi: InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)
InChi Key: IDQPVOFTURLJPT-UHFFFAOYSA-N
PubChem CID: 5173
MDL Number: MFCD00192455
USAGE: For Research Use Only! Not For Use in Humans. |